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Zepbound (Tirzepatide)

A Breakthrough in Medical Weight Loss

For many patients, traditional diets and exercise aren’t enough to achieve lasting results. Zepbound (tirzepatide) is a breakthrough FDA-approved medication that helps patients lose significant weight by targeting both appetite and metabolism.

At PrecisionMD Wellness and Weight Loss, our providers prescribe Zepbound for patients in our Decatur and Madison clinics and through telemedicine across Alabama, giving you access to one of the most effective weight loss tools available today.

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How Zepbound Works

Zepbound is a once-weekly injection that acts on two natural hormone pathways:
GLP-1 (glucagon-like peptide-1)

Reduces appetite, increases satiety, and stabilizes blood sugar

GIP (glucose-dependent insulinotropic polypeptide)

Improves insulin sensitivity and enhances the body’s ability to process food efficiently

This dual action makes Zepbound one of the most powerful weight loss medications currently available.

Benefits of Zepbound

Patients using Zepbound often experience:

  • Significant weight loss that continues over time
  • Reduced appetite and fewer cravings
  • Improved blood sugar control and metabolic health
  • Lower risk of conditions such as diabetes, heart disease, and high blood pressure

Who Is a Candidate for Zepbound?

You may qualify for Zepbound if you:
  • Have a BMI of 27 or higher with weight-related conditions such as diabetes, high blood pressure, or PCOS
  • Have a BMI of 30 or higher even without other medical concerns
  • Have moderate to severe obstructive sleep apnea, even in the absence of obesity
  • Struggle with appetite, cravings, or weight regain after dieting
  • Have a high body fat percentage or an increased waist circumference that places you at higher health risk, even if your BMI is considered normal

Frequently Asked Questions

Find quick answers to common questions about our services, products, and policies. This section is designed to help you get the information you need—fast and easy.
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How is Zepbound different from Wegovy?
Both are weekly GLP-1 injections, but Zepbound acts on both the GLP-1 and GIP pathways, while Wegovy only works on the GLP-1 pathway. Some patients respond better to one than the other.
No strict diet is required. At PrecisionMD, we don’t ask patients to follow rigid or highly restrictive meal plans. Instead, we emphasize balanced nutrition and sustainable habits that support long-term health and weight maintenance. While Zepbound helps regulate appetite and metabolism, the best results come when it’s combined with healthy lifestyle changes rather than short-term dieting.

Many patients notice changes in appetite or weight within the first 1–2 months, with continued results as treatment goes on. For others, progress may take longer. Every body responds differently based on metabolism, health history, and the medication dose.

Some patients use Zepbound long-term as part of a comprehensive weight management plan. Your provider will guide you based on your goals, progress, and overall health.
GLP-1 medications like Zepbound regulate appetite and metabolism. If you stop taking them without maintaining healthy, sustainable habits, weight regain is likely — much like how blood pressure or cholesterol often return if medication is stopped. At PrecisionMD, our goal is to combine medication with lifestyle strategies so you’re set up for long-term success, even if you eventually discontinue treatment.
Possibly, particularly if you also have risk factors such as insulin resistance, PCOS, sleep apnea, or other metabolic concerns. Your provider will review your medical history and lab results to determine if Zepbound is right for you.

At PrecisionMD, we work closely with your insurance company to determine if Zepbound is covered under your plan. Our team handles prior authorizations and, when needed, files appeals — we do everything possible to give you the best chance of approval.

Coverage depends on your specific plan. Some cover obesity medications, while others do not, or may exclude Zepbound specifically. If your insurance doesn’t cover it, you can still access direct-pay pricing through LillyDirect:

  • Starter dose: about $349 per month

  • All other doses: about $499 per month

This program allows you to get medication directly from the manufacturer’s pharmacy at a lower cash price when insurance coverage isn’t available.

 In clinical trials, patients taking Zepbound lost an average of 15–20% of their body weight over time when combined with healthy lifestyle changes. This makes Zepbound one of the most effective weight loss medications available today.

By comparison:

  • Wegovy (semaglutide) averages around 15% total body weight loss

  • Phentermine and Qsymia typically result in 5–10% weight loss

  • Contrave often leads to 5–8% weight loss

It’s important to remember that these are averages. Some patients lose significantly more, while others lose less, depending on factors like metabolism, starting weight, medical conditions, and consistency with lifestyle changes. At PrecisionMD, our goal is always to help you achieve safe, sustainable results that fit your unique health needs.

The most common side effects of Zepbound are mild digestive symptoms such as nausea, diarrhea, constipation, or stomach upset. These usually improve as your body adjusts, especially when the dose is increased gradually. Some patients may also experience fatigue or decreased appetite. Serious side effects are rare but can include pancreatitis or gallbladder problems. At PrecisionMD, we start with the lowest effective dose and increase slowly, monitoring your response closely. Our providers are here to help you manage any side effects and keep treatment safe and tolerable.

Zepbound at PrecisionMD

When you choose PrecisionMD for Zepbound treatment, you’ll receive:
  • A complete consultation and lab review
  • A prescription tailored to your health profile
  • Education on how to administer your injections
  • Follow-up visits every 4–12 weeks to track results and adjust your plan
  • Ongoing support for nutrition, lifestyle, and accountability
Take control of your health with one of the most effective weight loss medications available.
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Zepbound in Decatur, Madison, and Across Alabama

With locations in Decatur and Madison and telemedicine services statewide, PrecisionMD makes Zepbound accessible to patients across Huntsville, Athens, Cullman, Hartselle, Hazel Green, Harvest, and New Market.

Schedule your consultation today and see if Zepbound is the right fit for your weight loss journey.

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